1. WestCHEM, Department of Chemistry, Joseph Black Building, University of Glasgow, University Avenue, Glasgow, G12 8QQ, United Kingdom, School of Chemistry, University of Nottingham, University Park, Nottingham, NG7 2RD, United Kingdom, Merck Sharp and Dohme, Neuroscience Research Centre, Terlings Park, Harlow, Essex, CM20 2QR, United Kingdom, and Crop Protection Research Chemistry, Syngenta, Jealott's Hill International Research Centre, Bracknell, Berkshire, RG42 6EY, United Kingdom