Identification of Benzoxazin-3-one Derivatives as Novel, Potent, and Selective Nonsteroidal Mineralocorticoid Receptor Antagonists-Reference-Cited by-同舟云学术

Identification of Benzoxazin-3-one Derivatives as Novel, Potent, and Selective Nonsteroidal Mineralocorticoid Receptor Antagonists

Published:2011-11-29 Issue:24 Volume:54 Page:8616-8631
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hasui Tomoaki¹,Matsunaga Nobuyuki¹,Ora Taiichi¹,Ohyabu Norio¹,Nishigaki Nobuhiro¹,Imura Yoshimi¹,Igata Yumiko¹,Matsui Hideki¹,Motoyaji Takashi¹,Tanaka Toshimasa¹,Habuka Noriyuki¹,Sogabe Satoshi¹,Ono Midori¹,Siedem Christopher S.²,Tang Tony P.²,Gauthier Cassandra²,De Meese Lisa A.²,Boyd Steven A.²,Fukumoto Shoji¹

Affiliation:

1. Pharmaceutical Research Division, Takeda Pharmaceutical Company Ltd., 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan

2. Array BioPharma Inc., 3200 Walnut Street, Boulder, Colorado 80301, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm2011645

Reference32 articles.

1. Molecular Biology of Mineralocorticoid Metabolism

2. Aldosterone in Congestive Heart Failure