Omarigliptin (MK-3102): A Novel Long-Acting DPP-4 Inhibitor for Once-Weekly Treatment of Type 2 Diabetes-Reference-Cited by-同舟云学术

Omarigliptin (MK-3102): A Novel Long-Acting DPP-4 Inhibitor for Once-Weekly Treatment of Type 2 Diabetes

Published:2014-04-02 Issue:8 Volume:57 Page:3205-3212
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Biftu Tesfaye¹,Sinha-Roy Ranabir¹,Chen Ping¹,Qian Xiaoxia¹,Feng Dennis¹,Kuethe Jeffrey T.¹,Scapin Giovanna¹,Gao Ying Duo¹,Yan Youwei¹,Krueger Davida¹,Bak Annette¹,Eiermann George¹,He Jiafang¹,Cox Jason¹,Hicks Jacqueline¹,Lyons Kathy¹,He Huaibing¹,Salituro Gino¹,Tong Sharon¹,Patel Sangita¹,Doss George¹,Petrov Aleksandr¹,Wu Joseph¹,Xu Shiyao Sherrie¹,Sewall Charles¹,Zhang Xiaoping¹,Zhang Bei¹,Thornberry Nancy A.¹,Weber Ann E.¹

Affiliation:

1. Department of Discovery Chemistry, ‡Department of Metabolic Disorders, §Department of Pharmacology, ∥Department of Drug Metabolism, ⊥Basic Pharmaceutical Sciences, and #Department of Safety Assessment and Animal Resources, Merck & Co., Inc., Whitehouse Station, New Jersey 08889, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm401992e

Reference20 articles.

1. The incretin system and its role in type 2 diabetes mellitus

2. Minireview: Update on Incretin Biology: Focus on Glucagon-Like Peptide-1

3. Medicinal chemistry approaches to the inhibition of dipeptidyl peptidase-4 for the treatment of type 2 diabetes

4. Catalytic properties and inhibition of proline-specific dipeptidyl peptidases II, IV and VII

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