Pyridone-Conjugated Monobactam Antibiotics with Gram-Negative Activity-Reference-Cited by-同舟云学术

Pyridone-Conjugated Monobactam Antibiotics with Gram-Negative Activity

Published:2013-06-27 Issue:13 Volume:56 Page:5541-5552
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Brown Matthew F.¹,Mitton-Fry Mark J.¹,Arcari Joel T.¹,Barham Rose¹,Casavant Jeffrey¹,Gerstenberger Brian S.¹,Han Seungil¹,Hardink Joel R.¹,Harris Thomas M.¹,Hoang Thuy¹,Huband Michael D.¹,Lall Manjinder S.¹,Lemmon M. Megan¹,Li Chao¹,Lin Jian¹,McCurdy Sandra P.¹,McElroy Eric¹,McPherson Craig¹,Marr Eric S.¹,Mueller John P.¹,Mullins Lisa¹,Nikitenko Antonia A.¹,Noe Mark C.¹,Penzien Joseph¹,Plummer Mark S.¹,Schuff Brandon P.¹,Shanmugasundaram Veerabahu¹,Starr Jeremy T.¹,Sun Jianmin¹,Tomaras Andrew¹,Young Jennifer A.¹,Zaniewski Richard P.¹

Affiliation:

1. Worldwide Medicinal Chemistry, ‡Computational Chemistry, §Antibacterials Research Unit, ∥Pharmacokinetics, Dynamics & Metabolism, ⊥Structural Biology, Pfizer Global Research and Development, Eastern Point Road, Groton, Connecticut 06340, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400560z

Reference37 articles.

1. Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

2. Fix the antibiotics pipeline

3. Is drug release necessary for antimicrobial activity of siderophore-drug conjugates? Syntheses and biological studies of the naturally occurring salmycin “Trojan Horse” antibiotics and synthetic desferridanoxamine-antibiotic conjugates

4. Exploiting bacterial iron acquisition: siderophore conjugates

5. The New Monobactams: Chemistry and Biology

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