Effect of Structural and Conformation Modifications, Including Backbone Cyclization, of Hydrophilic Hexapeptides on Their Intestinal Permeability and Enzymatic Stability-Reference-Cited by-同舟云学术

Effect of Structural and Conformation Modifications, Including Backbone Cyclization, of Hydrophilic Hexapeptides on Their Intestinal Permeability and Enzymatic Stability

Published:2007-11-01 Issue:24 Volume:50 Page:6201-6211
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hess Shmuel¹,Ovadia Oded¹,Shalev Deborah E.¹,Senderovich Hanoch¹,Qadri Bashir¹,Yehezkel Tamar¹,Salitra Yoseph¹,Sheynis Tania¹,Jelinek Raz¹,Gilon Chaim¹,Hoffman Amnon¹

Affiliation:

1. Departments of Pharmaceutics and Organic Chemistry, and the Wolfson Centre for Applied Structural Biology, The Hebrew University of Jerusalem, Safra Campus, Jerusalem 91904, Israel, DeveloGen, Rehovot, Israel, and Department of Chemistry, Ben-Gurion University, Beersheba 84105, Israel

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm070836d

Reference48 articles.

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2. Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

3. Recognition of GPCRs by Peptide Ligands and Membrane Compartments theory: Structural Studies of Endogenous Peptide Hormones in Membrane Environment

4. Enteral absorption of octreotide: absorption enhancement by polyoxyethylene-24-cholesterol ether

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