1. School of Medicine and Pharmacology, University of Western Australia, Royal Perth Hospital Unit, Medical Research Foundation Building, Level 4, 50 Murray Street, Perth, WA 6000, Australia, School of Biomedical, Biochemical and Chemical Sciences, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia, and Institute of Food Research, Norwich Research Park, Norwich NR4 7UA, United Kingdom