Design, Synthesis, and In Vitro Activity of Peptidomimetic Inhibitors of Myeloid Differentiation Factor 88-Reference-Cited by-同舟云学术

Design, Synthesis, and In Vitro Activity of Peptidomimetic Inhibitors of Myeloid Differentiation Factor 88

Published:2008-02-15 Issue:5 Volume:51 Page:1189-1202
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Fantò Nicola¹,Gallo Grazia¹,Ciacci Andrea¹,Semproni Mauro¹,Vignola Davide¹,Quaglia Marco¹,Bombardi Valentina¹,Mastroianni Domenico¹,Zibella M. Pia¹,Basile Giancarlo¹,Sassano Marica¹,Ruggiero Vito¹,De Santis Rita¹,Carminati Paolo¹

Affiliation:

1. Research and Development, Sigma-Tau Industrie Farmaceutiche Riunite S.p.A., Pomezia (RM), Italy, and Tecnogen S.p.A., 81015 Piana di Monte Verna (CE), Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm070723u

Reference34 articles.

1. NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

2. Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases

3. The IL-1 receptor/toll-like receptor superfamily: crucial receptors for inflammation and host defense

4. Peptide-mediated Interference of TIR Domain Dimerization in MyD88 Inhibits Interleukin-1-dependent Activation of NF-κB

5. Differential Involvement of BB Loops of Toll-IL-1 Resistance (TIR) Domain-Containing Adapter Proteins in TLR4- versus TLR2-Mediated Signal Transduction

Cited by 29 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. MyD88 and Its Inhibitors in Cancer: Prospects and Challenges;Biomolecules;2024-05-07

2. The recent advance of Interleukin-1 receptor associated kinase 4 inhibitors for the treatment of inflammation and related diseases;European Journal of Medicinal Chemistry;2023-10

3. Design, Synthesis, and Bioevaluation of Novel MyD88 Inhibitor c17 against Acute Lung Injury Derived from the Virtual Screen;Journal of Medicinal Chemistry;2023-05-02

4. Discovery of a Novel MyD88 Inhibitor M20 and Its Protection Against Sepsis-Mediated Acute Lung Injury;Frontiers in Pharmacology;2021-11-29

5. Myeloid Differentiation Primary Response Protein 88 (MyD88): The Central Hub of TLR/IL-1R Signaling;Journal of Medicinal Chemistry;2020-09-15