3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a New Class of Synthetic Histone Deacetylase Inhibitors. 2. Effect of Pyrrole-C2 and/or -C4 Substitutions on Biological Activity-Reference-Cited by-同舟云学术

3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a New Class of Synthetic Histone Deacetylase Inhibitors. 2. Effect of Pyrrole-C2 and/or -C4 Substitutions on Biological Activity

Published:2004-01-21 Issue:5 Volume:47 Page:1098-1109
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Mai Antonello¹,Massa Silvio¹,Cerbara Ilaria¹,Valente Sergio¹,Ragno Rino¹,Bottoni Patrizia¹,Scatena Roberto¹,Loidl Peter¹,Brosch Gerald¹

Affiliation:

1. Dipartimento di Studi Farmaceutici, Università degli Studi di Roma “La Sapienza”, P. le A. Moro 5, 00185 Roma, Italy, Dipartimento Farmaco Chimico Tecnologico, Università degli Studi di Siena, via A. Moro, 53100 Siena, Italy, Dipartimento di Studi di Chimica e Tecnologia delle Sostanze Biologicamente Attive, Università degli Studi di Roma “La Sapienza”, P. le A. Moro 5, 00185 Roma, Italy, Istituto di Biochimica e Biochimica Clinica, Università Cattolica del Sacro Cuore, L. go F. Vito 1, 00168 Roma, Italy...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030990%2B

Reference63 articles.

1. Covalent modifications of histones: expression from chromatin templates

2. Histone acetylases and deacetylases in cell proliferation

3. The language of covalent histone modifications

4. What's Up and Down with Histone Deacetylation and Transcription?

5. The coregulator exchange in transcriptional functions of nuclear receptors

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