Catalytic, Enantioselective Synthesis of Taranabant, a Novel, Acyclic Cannabinoid-1 Receptor Inverse Agonist for the Treatment of Obesity
Author:
Affiliation:
1. Departments of Process Research, Medicinal Chemistry, Center for Material Science and Engineering, Chemical Process Development and Commercialization, Merck Research Laboratories, P.O. Box 2000, Rahway, New Jersey 07065, U.S.A.
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op700026n
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4. Discovery of N-[(1S,2S)-3-(4-Chlorophenyl)-2- (3-cyanophenyl)-1-methylpropyl]-2-methyl-2- {[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (MK-0364), a Novel, Acyclic Cannabinoid-1 Receptor Inverse Agonist for the Treatment of Obesity
5. Stereoselective Organic Synthesis via Dynamic Kinetic Resolution
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