Rapid Microscale Synthesis, a New Method for Lead Optimization Using Robotics and Solution Phase Chemistry: Application to the Synthesis and Optimization of Corticotropin-Releasing Factor1 Receptor Antagonists-Reference-Cited by-同舟云学术

Rapid Microscale Synthesis, a New Method for Lead Optimization Using Robotics and Solution Phase Chemistry: Application to the Synthesis and Optimization of Corticotropin-Releasing Factor1 Receptor Antagonists

Published:1996-01-01 Issue:22 Volume:39 Page:4354-4357
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Whitten Jeffrey P.¹,Xie Yun Feng¹,Erickson Philip E.¹,Webb Thomas R.¹,De Souza Errol B.¹,Grigoriadis Dimitri E.¹,McCarthy James R.¹

Affiliation:

1. Neurocrine Biosciences, 3050 Science Park Road, San Diego, California 92121

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm960148m

Reference45 articles.

1. Primary structure and functional expression of mouse pituitary and human brain corticotrophin releasing factor receptors

2. Cloning and functional expression of a rat brain corticotropin releasing factor (CRF) receptor.

3. Localization of novel corticotropin-releasing factor receptor (CRF2) mRNA expression to specific subcortical nuclei in rat brain: comparison with CRF1 receptor mRNA expression

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