Discovery of Sulfated Sterols from Marine Invertebrates as a New Class of Marine Natural Antagonists of Farnesoid-X-Receptor-Reference-Cited by-同舟云学术

Discovery of Sulfated Sterols from Marine Invertebrates as a New Class of Marine Natural Antagonists of Farnesoid-X-Receptor

Published:2011-02-10 Issue:5 Volume:54 Page:1314-1320
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Sepe Valentina¹,Bifulco Giuseppe²,Renga Barbara³,D’Amore Claudio³,Fiorucci Stefano³,Zampella Angela¹

Affiliation:

1. Dipartimento di Chimica delle Sostanze Naturali, Università di Napoli “Federico II”, via D. Montesano 49, 80131 Napoli, Italy

2. Dipartimento di Scienze Farmaceutiche, Università di Salerno, via Ponte don Melillo, 84084 Fisciano (SA), Italy

3. Dipartimento di Medicina Clinica e Sperimentale, Università di Perugia, Nuova Facoltà di Medicina e Chirurgia, Via Gerardo Dottori no. 1 S. Andrea delle Fratte, 06132 Perugia, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm101336m

Reference33 articles.

1. Endogenous Bile Acids Are Ligands for the Nuclear Receptor FXR/BAR

2. Bile Acids: Natural Ligands for an Orphan Nuclear Receptor

3. Identification of a Nuclear Receptor for Bile Acids

4. Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR

5. Targeting Farnesoid-X-Receptor: From Medicinal Chemistry to Disease Treatment

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