Expanding Reactivity in DNA-Encoded Library Synthesis via Reversible Binding of DNA to an Inert Quaternary Ammonium Support-Reference-Cited by-同舟云学术

Expanding Reactivity in DNA-Encoded Library Synthesis via Reversible Binding of DNA to an Inert Quaternary Ammonium Support

Published:2019-05-28 Issue:25 Volume:141 Page:9998-10006
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Flood Dillon T.¹,Asai Shota¹,Zhang Xuejing¹²,Wang Jie¹,Yoon Leonard¹,Adams Zoë C.¹,Dillingham Blythe C.¹,Sanchez Brittany B.³,Vantourout Julien C.¹,Flanagan Mark E.⁴,Piotrowski David W.⁴^ORCID,Richardson Paul⁵,Green Samantha A.¹,Shenvi Ryan A.¹^ORCID,Chen Jason S.³,Baran Phil S.¹^ORCID,Dawson Philip E.¹^ORCID

Affiliation:

1. Department of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States

2. The Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China

3. Automated Synthesis Facility, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States

4. Pfizer Medicinal Chemistry, Eastern Point Road, Groton, Connecticut 06340, United States

5. Pfizer Medicinal Chemistry, 10578 Science Center Drive, San Diego, California 92121, United States

Funder

Pfizer

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.9b03774

Reference46 articles.

1. Encoded combinatorial chemistry.

2. DNA-Encoded Chemical Libraries: A Selection System Based on Endowing Organic Compounds with Amplifiable Information

3. Design, synthesis and selection of DNA-encoded small-molecule libraries

4. Synthetic methods for the implementation of encoded combinatorial chemistry

5. A Brief History of the Development of Combinatorial Chemistry and the Emerging Need for DNA-Encoded Chemistry

Cited by 116 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Evolution of chemistry and selection technology for DNA-encoded library;Acta Pharmaceutica Sinica B;2024-02

2. Unexpected Cyclization Product Discovery from the Photoinduced Bioconjugation Chemistry between Tetrazole and Amine;Journal of the American Chemical Society;2024-01-08

3. Anhydrous Carbene Insertion Reactions: A Synthetic Platform for DNA‐Encoded Library;Advanced Synthesis & Catalysis;2023-12-14

4. Nickel-Catalyzed Radical Mechanisms: Informing Cross-Coupling for Synthesizing Non-Canonical Biomolecules;Accounts of Chemical Research;2023-11-30

5. Covalent Capture and Selection of DNA‐Encoded Chemical Libraries via Photo‐Activated Lysine‐Selective Crosslinkers;Chemistry – An Asian Journal;2023-10-09