Directed Evolution of a Cytochrome P450 Carbene Transferase for Selective Functionalization of Cyclic Compounds-Reference-Cited by-同舟云学术

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Directed Evolution of a Cytochrome P450 Carbene Transferase for Selective Functionalization of Cyclic Compounds

Published:2019-05-09 Issue:22 Volume:141 Page:8989-8995
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Brandenberg Oliver F.¹^ORCID,Chen Kai¹^ORCID,Arnold Frances H.¹^ORCID

Affiliation:

1. Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States

Funder

Division of Molecular and Cellular Biosciences

Schweizerischer Nationalfonds zur F?rderung der Wissenschaftlichen Forschung

Deutsche Forschungsgemeinschaft

Resnick Sustainability Institute for Science, Energy and Sustainability, California Institute of Technology

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.9b02931

Reference59 articles.

1. Heterocycles in drugs and drug discovery

2. Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

3. Mitigating Heterocycle Metabolism in Drug Discovery

4. From Oxiranes to Oligomers: Architectures of U.S. FDA Approved Pharmaceuticals Containing Oxygen Heterocycles

5. Natural product derived privileged scaffolds in drug discovery

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