Tunable Heteroaromatic Sulfones Enhance in-Cell Cysteine Profiling-Reference-Cited by-同舟云学术

Tunable Heteroaromatic Sulfones Enhance in-Cell Cysteine Profiling

Published:2019-12-27 Issue:4 Volume:142 Page:1801-1810
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Motiwala Hashim F.,Kuo Yu-Hsuan,Stinger Brittany L.,Palfey Bruce A.¹^ORCID,Martin Brent R.²^ORCID

Affiliation:

1. Department of Biological Chemistry, University of Michigan Medical School, 5220E MSRB III 1150 W. Medical Center Drive, Ann Arbor, Michigan 48109, United States,

2. Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, 428 Church Street, Ann Arbor, Michigan 48109, United States

Funder

University of Michigan

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.9b08831

Reference52 articles.

1. Methylsulfonyl Benzothiazole (MSBT): A Selective Protein Thiol Blocking Reagent

2. Rapid, Stable, Chemoselective Labeling of Thiols with Julia-Kocieński-like Reagents: A Serum-Stable Alternative to Maleimide-Based Protein Conjugation

3. Discovery of Heteroaromatic Sulfones As a New Class of Biologically Compatible Thiol-Selective Reagents

4. Improving the Serum Stability of Site-Specific Antibody Conjugates with Sulfone Linkers

5. Thiol-blocking electrophiles interfere with labeling and detection of protein sulfenic acids

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