Reactivity of an Unusual Amidase May Explain Colibactin’s DNA Cross-Linking Activity-Reference-Cited by-同舟云学术

Reactivity of an Unusual Amidase May Explain Colibactin’s DNA Cross-Linking Activity

Published:2019-06-28 Issue:29 Volume:141 Page:11489-11496
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Jiang Yindi¹,Stornetta Alessia²^ORCID,Villalta Peter W.²^ORCID,Wilson Matthew R.¹,Boudreau Paul D.¹,Zha Li¹,Balbo Silvia²^ORCID,Balskus Emily P.¹^ORCID

Affiliation:

1. Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, United States

2. Masonic Cancer Center, University of Minnesota, 2231 Sixth Street Southeast, Minneapolis, Minnesota 55455, United States

Funder

National Cancer Institute

American Cancer Society

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.9b02453

Reference36 articles.

1. Escherichia coli Induces DNA Double-Strand Breaks in Eukaryotic Cells

2. Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells

3. Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota

4. Microbial genomic analysis reveals the essential role of inflammation in bacteria-induced colorectal cancer

5. High Prevalence of Mucosa-Associated E. coli Producing Cyclomodulin and Genotoxin in Colon Cancer

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