O-Alkoxyamidine Prodrugs of Furamidine: In Vitro Transport and Microsomal Metabolism as Indicators of in Vivo Efficacy in a Mouse Model of Trypanosoma brucei rhodesiense Infection-Reference-Cited by-同舟云学术

O-Alkoxyamidine Prodrugs of Furamidine: In Vitro Transport and Microsomal Metabolism as Indicators of in Vivo Efficacy in a Mouse Model of Trypanosoma brucei rhodesiense Infection

Published:2004-07-16 Issue:17 Volume:47 Page:4335-4338
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ansede John H.¹,Anbazhagan Mariappan¹,Brun Reto¹,Easterbrook Judy D.¹,Hall James Edwin¹,Boykin David W.¹

Affiliation:

1. Division of Drug Delivery and Disposition, School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7360, Department of Chemistry, Georgia State University, Atlanta, Georgia 30303, and Swiss Tropical Institute, Basel, CH4002, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030604o

Reference12 articles.

1. Orally Active Fibrinogen Receptor Antagonists. 2. Amidoximes as Prodrugs of Amidines

2. Prodrugs for Amidines: Synthesis and Anti-Pneumocystis carinii Activity of Carbamates of 2,5-Bis(4-amidinophenyl)furan

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