Design and Evaluation of Fragment-Like Estrogen Receptor Tetrahydroisoquinoline Ligands from a Scaffold-Detection Approach-Reference-Cited by-同舟云学术

Design and Evaluation of Fragment-Like Estrogen Receptor Tetrahydroisoquinoline Ligands from a Scaffold-Detection Approach

Published:2011-03-07 Issue:7 Volume:54 Page:2005-2011
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Möcklinghoff Sabine¹²,van Otterlo Willem A. L.³⁴,Rose Rolf²,Fuchs Sascha¹,Zimmermann Tobias J.³,Dominguez Seoane Marta²,Waldmann Herbert³,Ottmann Christian²,Brunsveld Luc¹²

Affiliation:

1. Laboratory of Chemical Biology, Department of Biomedical Engineering, Technische Universiteit Eindhoven, Den Dolech 2, 5612AZ Eindhoven, The Netherlands

2. Chemical Genomics Centre of the Max-Planck Society, Otto-Hahn-Strasse 15, 44227 Dortmund, Germany

3. Max-Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany

4. Molecular Sciences Institute, School of Chemistry, University of the Witwatersrand, PO Wits, 2050 Johannesburg, South Africa

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm1011116

Reference39 articles.

1. A decade of fragment-based drug design: strategic advances and lessons learned

2. Drugs in other drugs: a new look at drugs as fragments

3. Recent Developments in Fragment-Based Drug Discovery

4. Charting biologically relevant chemical space: A structural classification of natural products (SCONP)

5. Detection and Assignment of Common Scaffolds in Project Databases of Lead Molecules

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