Confirmation of Primary Active Substances from High Throughput Screening of Chemical and Biological Populations:  A Statistical Approach and Practical Considerations

Author:

Zhang Ji-Hu1,Chung Thomas D.Y.1,Oldenburg Kevin R.1

Affiliation:

1. Leads Discovery, Experimental Station, DuPont Pharmaceuticals Company, P.O. Box 80400, Wilmington, Delaware 19880-0400

Publisher

American Chemical Society (ACS)

Subject

General Chemistry

Reference14 articles.

1. Dunnett, C. W.DrugScreening:TheNever-EndingSearchforNewandBetterDrugsinStatistics:AguidetotheUnknown; Tanur, J. M., et al., Eds.; Holden-Day:  San Francisco, 1978; pp 26−37.

2. High Throughput Screening

3. Toward a cDNA Map of the Human Genome

4. The GDBTM Human Genome Database Anno 1997

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