1. Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, Department of Molecular Biology and Microbiology, University of Central Florida, Orlando, Florida 32826, School of Chemistry and Material Engineering, Yunnan University, China, and Research center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China