Novel N-Linked Aminopiperidine-Based Gyrase Inhibitors with Improved hERG and in Vivo Efficacy against Mycobacterium tuberculosis-Reference-Cited by-同舟云学术

Novel N-Linked Aminopiperidine-Based Gyrase Inhibitors with Improved hERG and in Vivo Efficacy against Mycobacterium tuberculosis

Published:2014-05-23 Issue:11 Volume:57 Page:4889-4905
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hameed P Shahul,Patil Vikas,Solapure Suresh,Sharma Umender,Madhavapeddi Prashanti,Raichurkar Anandkumar,Chinnapattu Murugan,Manjrekar Praveena,Shanbhag Gajanan,Puttur Jayashree,Shinde Vikas,Menasinakai Sreenivasaiah,Rudrapatana Suresh,Achar Vijayashree,Awasthy Disha,Nandishaiah Radha,Humnabadkar Vaishali,Ghosh Anirban,Narayan Chandan,Ramya V. K.,Kaur Parvinder,Sharma Sreevalli,Werngren Jim,Hoffner Sven,Panduga Vijender,Kumar C. N. Naveen,Reddy Jitendar,Kumar KN Mahesh,Ganguly Samit,Bharath Sowmya,Bheemarao Ugarkar,Mukherjee Kakoli,Arora Uma,Gaonkar Sheshagiri,Coulson Michelle¹,Waterson David,Sambandamurthy Vasan K.,de Sousa Sunita M.

Affiliation:

1. Safety Assessment, AstraZeneca, Alderley Park, Macclesfield, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm500432n

Reference43 articles.

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2. World Health Organization. Multidrug and extensively drug-resistant TB (M/XDR-TB); WHO 2010 Global report on surveillance and response;WHO:Geneva, 2010.

3. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

4. Current possibilities and unresolved issues of drug target validation inMycobacterium tuberculosis

5. Moxifloxacin versus Ethambutol in the First 2 Months of Treatment for Pulmonary Tuberculosis

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