Discovery of the First N-Substituted 4β-Methyl-5-(3-hydroxyphenyl)morphan To Possess Highly Potent and Selective Opioid δ Receptor Antagonist Activity-Reference-Cited by-同舟云学术

Discovery of the First N-Substituted 4β-Methyl-5-(3-hydroxyphenyl)morphan To Possess Highly Potent and Selective Opioid δ Receptor Antagonist Activity

Published:2003-12-11 Issue:2 Volume:47 Page:281-284
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Carroll F. Ivy¹,Zhang Li¹,Mascarella S. Wayne¹,Navarro Hernán A.¹,Rothman Richard B.¹,Cantrell Buddy E.¹,Zimmerman Dennis M.¹,Thomas James B.¹

Affiliation:

1. Chemistry and Life Sciences, Research Triangle Institute, Research Triangle Park, North Carolina 27709; Clinical Psychopharmacology Section, IRP, NIDA, NIH, 5500 Nathan Shock Drive, Baltimore, Maryland 21224; and Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana 46285

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030419a

Reference33 articles.

1. Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the µ-opioid-receptor gene

2. 2002 Medicinal Chemistry Division Award Address: Monoamine Transporters and Opioid Receptors. Targets for Addiction Therapy

3. Non-peptide δ opioid agonists and antagonists

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Correction: Tanguturi et al. Discovery of Novel Delta Opioid Receptor (DOR) Inverse Agonist and Irreversible (Non-Competitive) Antagonists. Molecules 2021, 26, 6693;Molecules;2022-03-18

2. δ Opioid Receptor Inverse Agonists and their In Vivo Pharmacological Effects;Current Topics in Medicinal Chemistry;2020-12-03

3. An environmentally benign double Michael addition reaction of heterocyclic ketene aminals with quinone monoketals for diastereoselective synthesis of highly functionalized morphan derivatives in water;Green Chemistry;2017

4. Molecular Pharmacology ofδ-Opioid Receptors;Pharmacological Reviews;2016-06-24

5. Diastereoselective Synthesis of 3,4-Benzomorphan Derivatives via Tandem [5 + 1]/Hemiaminalization of (2-Aminoaryl)divinyl Ketones;Organic Letters;2016-01-06