An environmentally benign double Michael addition reaction of heterocyclic ketene aminals with quinone monoketals for diastereoselective synthesis of highly functionalized morphan derivatives in water

Author:

Ma Yu-Lu12345,Wang Kai-Min12345,Huang Rong12345,Lin Jun12345ORCID,Yan Sheng-Jiao12345ORCID

Affiliation:

1. Key Laboratory of Medicinal Chemistry for Natural Resource (Yunnan University)

2. Ministry of Education

3. School of Chemical Science and Technology

4. Yunnan University

5. Kunming

Abstract

This effort involved an efficient and concise one-pot procedure for the synthesis of morphans based on quinone monoketals 1 reacting with HKAs 2.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

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