Structure-Based Design and Synthesis of Novel Potent Na+,K+-ATPase Inhibitors Derived from a 5α,14α-Androstane Scaffold as Positive Inotropic Compounds-Reference-Cited by-同舟云学术

Structure-Based Design and Synthesis of Novel Potent Na+,K+-ATPase Inhibitors Derived from a 5α,14α-Androstane Scaffold as Positive Inotropic Compounds

Published:2003-07-23 Issue:17 Volume:46 Page:3644-3654
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

De Munari Sergio¹,Cerri Alberto¹,Gobbini Mauro¹,Almirante Nicoletta¹,Banfi Leonardo¹,Carzana Giulio¹,Ferrari Patrizia¹,Marazzi Giuseppe¹,Micheletti Rosella¹,Schiavone Antonio¹,Sputore Simona¹,Torri Marco¹,Zappavigna Maria Pia¹,Melloni Piero¹

Affiliation:

1. Departments of Medicinal Chemistry and Cardiovascular Pharmacology, Prassis Istituto di Ricerche Sigma-Tau, Via Forlanini 3, 20019 Settimo Milanese (MI), Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030830y

Reference24 articles.

1. A New Approach to the Design of Novel Inhibitors of Na+,K+-ATPase: 17α-Substituted Seco-D 5β-Androstane as Cassaine Analogues

2. 17α-O-(Aminoalkyl)oxime Derivatives of 3β,14β-Dihydroxy-5β-androstane and 3β-Hydroxy-14-oxoseco-D-5β-androstane as Inhibitors of Na+,K+-ATPase at the Digitalis Receptor

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