Versatile and Efficient Solid-Phase Syntheses of Pyrazoles and Isoxazoles
Author:
Affiliation:
1. Department of Molecular Design and Diversity, Merck Research Laboratories, P.O. Box 2000 RY800-C306, Rahway, New Jersey 07065
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol006197h
Reference3 articles.
1. Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors: Identification of 4-[5-(4-Methylphenyl)-3- (trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib)
2. Solid support synthesis of highly functionalized pyrazoles and isoxazoles; Scaffolds for molecular diversity
3. (b) Cody, D. R.; DeWitt, S. H.; Hodges, J. C.; Roth, B. D.; Schroeder, M. C.; Stankovic, C. J.; Moos, W. H.; Pavia, M. R.; Kiely, J. S. WO 94/08711, 1994.
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