1. Laboratory of Pharmaceutical Biology and Pharmacology and Laboratory of Toxicology and Food Chemistry, Katholieke Universiteit Leuven, Van Evenstraat 4, B-3000 Leuven, Belgium; Laboratory of Medicinal Chemistry, Katholieke Universiteit Leuven, Rega Institute, B-3000 Leuven, Belgium; and Interdisciplinary Research Center, Katholieke Universiteit Leuven Campus Kortrijk, Universitaire Campus, B-8500 Kortrijk, Belgium