Potent Tetracyclic Guanine Inhibitors of PDE1 and PDE5 Cyclic Guanosine Monophosphate Phosphodiesterases with Oral Antihypertensive Activity-Reference-Cited by-同舟云学术

Potent Tetracyclic Guanine Inhibitors of PDE1 and PDE5 Cyclic Guanosine Monophosphate Phosphodiesterases with Oral Antihypertensive Activity

Published:1997-07-01 Issue:14 Volume:40 Page:2196-2210
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ahn Ho-Sam¹,Bercovici Ana¹,Boykow George¹,Bronnenkant Alan¹,Chackalamannil Samuel¹,Chow Jason¹,Cleven Renee¹,Cook John¹,Czarniecki Michael¹,Domalski Carol¹,Fawzi Ahmad¹,Green Michael¹,Gündes Asli¹,Ho Ginny¹,Laudicina Malvina¹,Lindo Neil¹,Ma Ke¹,Manna Mahua¹,McKittrick Brian¹,Mirzai Bita¹,Nechuta Terry¹,Neustadt Bernard¹,Puchalski Chester¹,Pula Kathryn¹,Silverman Lisa¹,Smith Elizabeth¹,Stamford Andrew¹,Tedesco Richard P.¹,Tsai Hsingan¹,Tulshian Deen¹,Vaccaro Henry¹,Watkins Robert W.¹,Weng Xiaoyu¹,Witkowski Joseph T.¹,Xia Yan¹,Zhang Hongtao¹

Affiliation:

1. Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9608467

Reference20 articles.

1. Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms

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