Synthesis of New Dihydroindeno[1,2-c]isoquinoline and Indenoisoquinolinium Chloride Topoisomerase I Inhibitors Having High in Vivo Anticancer Activity in the Hollow Fiber Animal Model-Reference-Cited by-同舟云学术

Synthesis of New Dihydroindeno[1,2-c]isoquinoline and Indenoisoquinolinium Chloride Topoisomerase I Inhibitors Having High in Vivo Anticancer Activity in the Hollow Fiber Animal Model

Published:2001-12-06 Issue:1 Volume:45 Page:242-249
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Jayaraman Muthusamy¹,Fox Brian M.¹,Hollingshead Melinda¹,Kohlhagen Glenda¹,Pommier Yves¹,Cushman Mark¹

Affiliation:

1. Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, Indiana 47907, Biological Testing Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Fairview Center, Suite 205, 1003 West Seventh Street, Frederick, Maryland 21701, and Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm000498f

Reference16 articles.

1. Synthesis of Cytotoxic Indenoisoquinoline Topoisomerase I Poisons

2. Phosphorus pentoxide-methanesulfonic acid. Convenient alternative to polyphosphoric acid

3. Preparation and antileukemic activity of some alkoxybenzo[c]phenanthridinium salts and corresponding dihydro derivatives

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