Synthesis of Cytotoxic Indenoisoquinoline Topoisomerase I Poisons-Reference-Cited by-同舟云学术

Synthesis of Cytotoxic Indenoisoquinoline Topoisomerase I Poisons

Published:1999-01-06 Issue:3 Volume:42 Page:446-457
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Strumberg Dirk¹,Pommier Yves¹,Paull Kenneth¹,Jayaraman Muthusamy¹,Nagafuji Pamela¹,Cushman Mark¹

Affiliation:

1. Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy, Purdue University, West Lafayette, Indiana 47906, Information Technology Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland 20892, and Laboratory of Molecular Pharmacology, Division of Basic Sciences, National Cancer Institute, Bethesda, Maryland 20892-4255

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9803323

Reference24 articles.

1. Display and Analysis of Patterns of Differential Activity of Drugs Against Human Tumor Cell Lines: Development of Mean Graph and COMPARE Algorithm

2. Paull, K. D.; Hamel, E.; Malspeis, L.Prediction of Biochemical Mechanism ofAction from the In Vitro Antitumor Screen of the National Cancer Institute; American Chemical Society: Washington, DC, 1995; pp 8−45.

3. Protein-Linked DNA Strand Breaks Induced by NSC 314622, a Novel Noncamptothecin Topoisomerase I Poison

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