Practical Synthesis of 3-Amino-4,5-dimethylisoxazole from 2-Methyl-2-butenenitrile and Acetohydroxamic Acid
Author:
Affiliation:
1. Discovery Chemistry, Bristol-Myers Squibb Pharmaceutical Research Institute, P.O. Box 4000, Princeton, New Jersey 08543, U.S.A.
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op060239l
Reference17 articles.
1. Biphenylsulfonamide Endothelin Receptor Antagonists. 2. Discovery of 4‘-Oxazolyl Biphenylsulfonamides as a New Class of Potent, Highly Selective ETA Antagonists
2. Dual Angiotensin II and Endothelin A Receptor Antagonists: Synthesis of 2‘-Substituted N-3-Isoxazolyl Biphenylsulfonamides with Improved Potency and Pharmacokinetics
3. Justoni, R.Rend., Ist. Lomb. Sci.1938,71, 407−424;Chem. Abstr.1940,34, 21257.
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1. Isoxazoles;Comprehensive Heterocyclic Chemistry IV;2022
2. Efficient Transformation of Alkyl 3-nitro-5-(aryl/alkyl)isoxazole-4-carboxylates into 3-amino- and 3-hydrazinyl-5-aryl/alkyl-isoxazole-4-carboxylates in Aqueous Solution;Advanced Synthesis & Catalysis;2017-09-29
3. Isobaric Vapor–Liquid Equilibria for Binary Mixtures of Z,E-2-Methyl-2-butenenitrile, R,S-4-Vinyl-1-cyclohexene, and Z,E-3-Pentenenitrile;Journal of Chemical & Engineering Data;2016-09-19
4. N-Hydroxyacetamide;Encyclopedia of Reagents for Organic Synthesis;2008-09-15
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