Mechanism of the Orotidine 5′-Monophosphate Decarboxylase-Catalyzed Reaction: Effect of Solvent Viscosity on Kinetic Constants
Author:
Affiliation:
1. Departments of Biochemistry and Chemistry, University of Illinois at Urbana−Champaign, Urbana, Illinois 61801
2. Department of Chemistry, University at Buffalo, Buffalo, New York 14260
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi9006226
Reference24 articles.
1. Dissecting the Total Transition State Stabilization Provided by Amino Acid Side Chains at Orotidine 5′-Monophosphate Decarboxylase: A Two-Part Substrate Approach
2. A Proficient Enzyme
3. Catalytic Proficiency: The Unusual Case of OMP Decarboxylase
4. Equilibrium of Formation of the 6-Carbanion of UMP, a Potential Intermediate in the Action of OMP Decarboxylase
5. Anatomy of a proficient enzyme: The structure of orotidine 5'-monophosphate decarboxylase in the presence and absence of a potential transition state analog
Cited by 33 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Kinetic solvent viscosity effects uncover an internal isomerization of the enzyme-substrate complex in Pseudomonas aeruginosa PAO1 NADH:Quinone oxidoreductase;Archives of Biochemistry and Biophysics;2022-09
2. Implications for an Imidazole-2-yl Carbene Intermediate in the Rhodanase-Catalyzed C–S Bond Formation Reaction of Anaerobic Ergothioneine Biosynthesis;ACS Catalysis;2021-03-01
3. Orotidine 5′-Monophosphate Decarboxylase: The Operation of Active Site Chains Within and Across Protein Subunits;Biochemistry;2020-05-06
4. Role of the Carboxylate in Enzyme-Catalyzed Decarboxylation of Orotidine 5′-Monophosphate: Transition State Stabilization Dominates Over Ground State Destabilization;Journal of the American Chemical Society;2019-07-31
5. Protein Flexibility and Stiffness Enable Efficient Enzymatic Catalysis;Journal of the American Chemical Society;2019-01-31
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3