Discovery of Cell-Permeable Non-Peptide Inhibitors of β-Secretase by High-Throughput Docking and Continuum Electrostatics Calculations-Reference-Cited by-同舟云学术

Discovery of Cell-Permeable Non-Peptide Inhibitors of β-Secretase by High-Throughput Docking and Continuum Electrostatics Calculations

Published:2005-07-08 Issue:16 Volume:48 Page:5108-5111
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Huang Danzhi¹,Lüthi Urs¹,Kolb Peter¹,Edler Karin¹,Cecchini Marco¹,Audetat Stephan¹,Barberis Alcide¹,Caflisch Amedeo¹

Affiliation:

1. Department of Biochemistry, University of Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland, and ESBATech AG, Wagistrasse 21, CH-8952 Zürich-Schlieren, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm050499d

Reference33 articles.

1. β-Secretase inhibition for the treatment of Alzheimer's disease – promise and challenge

2. Translating cell biology into therapeutic advances in Alzheimer's disease

3. Self-Propagating, Molecular-Level Polymorphism in Alzheimer's ß-Amyloid Fibrils

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