The Role of pH in the Glucuronidation of Raloxifene, Mycophenolic Acid and Ezetimibe-Reference-Cited by-同舟云学术

The Role of pH in the Glucuronidation of Raloxifene, Mycophenolic Acid and Ezetimibe

Published:2009-06-08 Issue:4 Volume:6 Page:1216-1227
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Chang Jae H.¹,Yoo Phillip¹,Lee Theresa¹,Klopf Wendy¹,Takao Denise¹

Affiliation:

1. Non-Clinical Safety, Department of Drug Metabolism and Pharmacokinetics, Roche Palo Alto, Palo Alto, California 94304, and Ernest Mario School of Pharmacy, Rutgers University, 160 Frelinghuysen Road, Piscataway, New Jersey 08854-8020

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp900065b

Reference47 articles.

1. STRUCTURAL AND FUNCTIONAL STUDIES OF UDP-GLUCURONOSYLTRANSFERASES*

2. Distribution of UDP-glucuronosyltransferase and its endogenous substrate uridine 5?-diphosphoglucuronic acid in human tissues

3. Human UDP-Glucuronosyltransferases: Metabolism, Expression, and Disease

4. In vitro–in vivo correlation for drugs and other compounds eliminated by glucuronidation in humans: Pitfalls and promises

5. DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS

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