Crosstalk of physiological pH and chemical pKa under the umbrella of physiologically based pharmacokinetic modeling of drug absorption, distribution, metabolism, excretion, and toxicity-Reference-Cited by-同舟云学术

Crosstalk of physiological pH and chemical pKa under the umbrella of physiologically based pharmacokinetic modeling of drug absorption, distribution, metabolism, excretion, and toxicity

Published:2021-07-31 Issue:9 Volume:17 Page:1103-1124
ISSN:1742-5255
Container-title:Expert Opinion on Drug Metabolism & Toxicology
language:en
Short-container-title:Expert Opinion on Drug Metabolism & Toxicology

Author:

Gaohua Lu¹^ORCID,Miao Xiusheng²^ORCID,Dou Liu³

Affiliation:

1. Research & Early Development, Princeton, New Jersey, USA

2. Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Collegeville, Pennsylvania, USA

3. School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Guangzhou, Guangdong, China

Publisher

Informa UK Limited

Subject

Pharmacology,Toxicology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/17425255.2021.1951223

Reference143 articles.

1. Cocaine: What is the Crack? A Brief History of the Use of Cocaine as an Anesthetic

2. The Mode of Action of Local Anaesthetics

3. Ionization, pH and Biological Activity

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