Structure–Activity Relationship of Adenosine 5′-diphosphoribose at the Transient Receptor Potential Melastatin 2 (TRPM2) Channel: Rational Design of Antagonists-Reference-Cited by-同舟云学术

Structure–Activity Relationship of Adenosine 5′-diphosphoribose at the Transient Receptor Potential Melastatin 2 (TRPM2) Channel: Rational Design of Antagonists

Published:2013-12-13 Issue:24 Volume:56 Page:10079-10102
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Moreau Christelle¹,Kirchberger Tanja²,Swarbrick Joanna M.¹,Bartlett Stephen J.¹,Fliegert Ralf²,Yorgan Timur²,Bauche Andreas²,Harneit Angelika²,Guse Andreas H.²,Potter Barry V. L.¹

Affiliation:

1. Wolfson Laboratory of Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom

2. The Calcium Signalling Group, Department of Biochemistry and Molecular Cell Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, D-20246 Hamburg, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm401497a

Reference62 articles.

1. TRP channels as cellular sensors

2. ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

3. The Crystal Structure and Mutational Analysis of Human NUDT9

4. Immunocyte Ca 2+ Influx System Mediated by LTRPC2

5. TRPM2 Ca2+ permeable cation channels: from gene to biological function

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