Bifunctional Inhibition of Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Mechanism and Proof-of-Concept as a Novel Therapeutic Design Strategy

Author:

Bailey Christopher M.,Sullivan Todd J.,Iyidogan Pinar,Tirado-Rives Julian,Chung Raymond,Ruiz-Caro Juliana,Mohamed Ebrahim1,Jorgensen William,Hunter Roger1,Anderson Karen S.

Affiliation:

1. Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference62 articles.

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2. World Health Organization. Antiretroviraltherapy for HIV infection in adults and adolescents:Recommendations for a public health approach, (2010) revision.http://www.who.int/hiv/pub/arv/adult2010/en/index.html(accessed January 14, 2013).

3. Molecular basis of human immunodeficiency virus drug resistance: An update

4. Clinical Significance and Biological Basis of HIV Drug Resistance

5. Retrovirus mutation rates and their role in genetic variation.

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