Chemical and Enzymatic Synthesis of 2-(2-Carbamoylethyl)- and 2-(2-Carboxyethyl)aziridines and Their Conversion into δ-Lactams and γ-Lactones-Reference-Cited by-同舟云学术

Chemical and Enzymatic Synthesis of 2-(2-Carbamoylethyl)- and 2-(2-Carboxyethyl)aziridines and Their Conversion into δ-Lactams and γ-Lactones

Published:2011-12-09 Issue:1 Volume:14 Page:106-109
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Vervisch Karel¹,D’hooghe Matthias¹,Rutjes Floris P. J. T.²,De Kimpe Norbert¹

Affiliation:

1. Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium

2. Institute for Molecules and Materials, Radboud University Nijmegen, Heyendaalseweg 135, NL-6525 AJ Nijmegen, The Netherlands

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol202888j

Reference46 articles.

1. Nitrile-Containing Pharmaceuticals: Efficacious Roles of the Nitrile Pharmacophore

2. aKlempier, N.; Winkler, M.InModern Biocatalysis: Stereoselective and Environmentally Friendly Reactions;Fessner, W.D.; Anthonsen, T., Eds.Wiley-VCH:Weinheim, Germany, 2009; p247.

3. Biocatalysis in Organic Synthesis: The Use of Nitrile- and Amide-hydrolyzing Microorganisms

4. An effective approach to the enantiomers of alicyclic β-aminonitriles by using lipase catalysis

5. Synthesis and microbial transformation of β-amino nitriles

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