Synthesis of Fluorosugar Analogues of 2,5,6-Trichloro-1-(β-d-ribofuranosyl)benzimidazole as Antivirals with Potentially Increased Glycosidic Bond Stability-Reference-Cited by-同舟云学术

Synthesis of Fluorosugar Analogues of 2,5,6-Trichloro-1-(β-d-ribofuranosyl)benzimidazole as Antivirals with Potentially Increased Glycosidic Bond Stability

Published:2000-05-16 Issue:12 Volume:43 Page:2473-2478
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gudmundsson Kristjan S.¹,Freeman George A.¹,Drach John C.¹,Townsend Leroy B.¹

Affiliation:

1. Department of Medicinal Chemistry, College of Pharmacy, Department of Chemistry, College of Literature, Sciences and Arts, and Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, Michigan 48109-1065, and Division of Medicinal Chemistry, Glaxo Wellcome Inc., Research Triangle Park, North Carolina 27709

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm990219s

Reference24 articles.

1. (S)-1-[3-Hydroxy-2-(Phosphonylmethoxy)propyl]cytosine (Cidofovir): Results of a Phase I/II Study of a Novel Antiviral Nucleotide Analogue

2. "The end of innocence" revisited: resistance of herpesviruses to antiviral drugs

3. Benzimidazole nucleosides, nucleotides, and related derivatives

4. Design, Synthesis, and Antiviral Activity of Certain 2,5,6-Trihalo-1-(.beta.-D-ribofuranosyl)benzimidazoles

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