Detection of Extracellular RNAs in Cancer and Viral Infection via Tethered Cationic Lipoplex Nanoparticles Containing Molecular Beacons

Author:

Wu Yun1,Kwak Kwang Joo1,Agarwal Kitty12,Marras Alexander3,Wang Chao4,Mao Yicheng15,Huang Xiaomeng1,Ma Junyu1,Yu Bo6,Lee Robert15,Vachani Anil7,Marcucci Guido8,Byrd John C.9,Muthusamy Natarajan10,Otterson Gregory11,Huang Kun12,Castro Carlos E.13,Paulaitis Michael113,Nana-Sinkam Serge P.14,Lee L. James113

Affiliation:

1. Center for Affordable Nanoengineering of Polymeric Biomedical Devices, The Ohio State University, 174 West 18th Avenue, Room 1012, Columbus, Ohio 43212, United States

2. Department of Chemistry and Biochemistry, The Ohio State University, 100 West 18th Avenue, Columbus, Ohio 43210, United States

3. Department of Mechanical Engineering, The Ohio State University, 201 West 19th Avenue, Room E328, Columbus, Ohio 43212, United States

4. Department of Electrical and Computer Engineering, The Ohio State University, 460 West 12th Avenue, Room 336, Columbus, Ohio 43210, United States

5. College of Pharmacy, The Ohio State University, 500 West 12th Avenue, Room 542, Columbus, Ohio 43210, United States

6. Nanomaterial Innovation Ltd. 1109 Millcreek Lane, Columbus, Ohio 43220, United States

7. Division of Pulmonary Allergy and Critical Care, University of Pennsylvania, 1016E Abramson Research Center, 3615 Civic Center Boulevard, Philadelphia, Pennsylvania 19104, United States

8. Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, 460 West 12th Avenue, Room 898, Columbus, Ohio 43210, United States

9. Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, 320 West 10th Avenue, Room B302, Columbus, Ohio 43210, United States

10. Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, 410 West 12th Avenue, Room 455E, Columbus, Ohio 43210, United States

11. Department of Internal Medicine, College of Medicine, The Ohio State University, 320 West 10th Avenue, Room B450, Columbus, Ohio 43210, United States

12. Department of Biomedical Informatics, College of Medicine, The Ohio State University, 333 West 10th Avenue, Room 3190, Columbus, Ohio 43210, United States

13. William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, 140 West 19th Avenue, Room 125A, Columbus, Ohio 43212, United States

14. Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, DHLRI, The Ohio State University, 473 West 12th Avenue, Room 201, Columbus, Ohio 43210, United States

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

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