1. School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan 100, Republic of China, Institute of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung, Taiwan 804, Republic of China, Department of Pharmacy, Tajen University, Yen-Pou, Ping Tung Shien, Taiwan, Republic of China, and National Research Institute of Chinese Medicine, Taipei, 112, Taiwan, Republic of China