Evolution from a Natural Flavones Nucleus to Obtain 2-(4-Propoxyphenyl)quinoline Derivatives As Potent Inhibitors of the S. aureus NorA Efflux Pump-Reference-Cited by-同舟云学术

Evolution from a Natural Flavones Nucleus to Obtain 2-(4-Propoxyphenyl)quinoline Derivatives As Potent Inhibitors of the S. aureus NorA Efflux Pump

Published:2011-08-03 Issue:16 Volume:54 Page:5722-5736
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Sabatini Stefano¹,Gosetto Francesca¹,Manfroni Giuseppe¹,Tabarrini Oriana¹,Kaatz Glenn W.²,Patel Diixa²,Cecchetti Violetta¹

Affiliation:

1. Dipartimento di Chimica e Tecnologia del Farmaco, Università degli Studi di Perugia, 06123 Perugia, Italy

2. Department of Internal Medicine, Division of Infectious Diseases, School of Medicine, Wayne State University, and the John D. Dingell Department of Veteran Affairs Medical Center, Detroit, Michigan 48201, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm200370y

Reference72 articles.

1. The end of an era?

2. Antibacterial discovery and development—the failure of success?

3. Desperately Seeking New Antibiotics

4. Hospitalizations and Deaths Caused by Methicillin-ResistantStaphylococcus aureus, United States, 1999–2005

5. Invasive Methicillin-Resistant Staphylococcus aureus Infections in the United States

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