Rational Domain Swaps Decipher Programming in Fungal Highly Reducing Polyketide Synthases and Resurrect an Extinct Metabolite-Reference-Cited by-同舟云学术

Rational Domain Swaps Decipher Programming in Fungal Highly Reducing Polyketide Synthases and Resurrect an Extinct Metabolite

Published:2011-09-26 Issue:41 Volume:133 Page:16635-16641
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Fisch Katja M.¹,Bakeer Walid¹²,Yakasai Ahmed A.¹,Song Zhongshu¹,Pedrick Jennifer¹,Wasil Zahida¹,Bailey Andrew M.³,Lazarus Colin M.³,Simpson Thomas J.¹,Cox Russell J.¹

Affiliation:

1. School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, U.K.

2. Faculty of Pharmacy, Beni Suef University, Salah Salem Street, Beni Suef 32514, Egypt

3. School of Biological Sciences, University of Bristol, Woodland Road, Bristol BS8 1UG, U.K.

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja206914q

Reference34 articles.

1. Polyketides, proteins and genes in fungi: programmed nano-machines begin to reveal their secrets

2. Polyketide biosynthesis: a millennium review

3. Identification of a starter unit acyl-carrier protein transacylase domain in an iterative type I polyketide synthase

4. Structural basis for biosynthetic programming of fungal aromatic polyketide cyclization

5. Deconstruction of Iterative Multidomain Polyketide Synthase Function

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