Enzymatic- and Iridium-Catalyzed Asymmetric Synthesis of a Benzothiazepinylphosphonate Bile Acid Transporter Inhibitor-Reference-Cited by-同舟云学术

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Enzymatic- and Iridium-Catalyzed Asymmetric Synthesis of a Benzothiazepinylphosphonate Bile Acid Transporter Inhibitor

Published:2013-12-04 Issue:24 Volume:78 Page:12726-12734
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Cowan David J.¹,Collins Jon L.¹,Mitchell Mark B.¹,Ray John A.¹,Sutton Peter W.²,Sarjeant Amy A.³,Boros Eric E.¹

Affiliation:

1. GlaxoSmithKline Research & Development, Five Moore Drive, Research Triangle Park, North Carolina 27709, United States

2. GlaxoSmithKline Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, United Kingdom

3. Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo402311e

Reference30 articles.

1. Bile Acid Transporters: Structure, Function, Regulation and Pathophysiological Implications

2. Bile acid transporters in health and disease

3. Bile acid transporters

4. A novel class of apical sodium co-dependent bile acid transporter inhibitors: The 1,2-Benzothiazepines

5. A novel class of apical sodium-dependent bile acid transporter inhibitors: the amphiphilic 4-oxo-1-phenyl-1,4-dihydroquinoline derivatives

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