Tetrahydroquinoline Derivatives as Potent and Selective Factor XIa Inhibitors-Reference-Cited by-同舟云学术

Tetrahydroquinoline Derivatives as Potent and Selective Factor XIa Inhibitors

Published:2014-01-17 Issue:3 Volume:57 Page:955-969
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Quan Mimi L.¹,Wong Pancras C.¹,Wang Cailan¹,Woerner Francis¹,Smallheer Joanne M.¹,Barbera Frank A.¹,Bozarth Jeffrey M.¹,Brown Randi L.¹,Harpel Mark R.¹,Luettgen Joseph M.¹,Morin Paul E.¹,Peterson Tara¹,Ramamurthy Vidhyashankar¹,Rendina Alan R.¹,Rossi Karen A.¹,Watson Carol A.¹,Wei Anzhi¹,Zhang Ge¹,Seiffert Dietmar¹,Wexler Ruth R.¹

Affiliation:

1. Discovery Chemistry and Cardiovascular Biology, Research and Development, Bristol-Myers Squibb Company, 311 Pennington-Rocky Hill Road, Pennington, New Jersey 08543, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm401670x

Reference57 articles.

1. Arterial thrombosis—insidious, unpredictable and deadly

2. bGlobal Status Report on Noncommunicable Diseases 2010.WHO Press:Geneva, Switzerland, 2011.

3. cWHO Fact Sheet No.310;WHO:Geneva, Switzerland, June 2011.

4. Pharmacology and Management of the Vitamin K Antagonists

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