Synthesis and Biological Evaluation of 14-Alkoxymorphinans. 20. 14-Phenylpropoxymetopon: An Extremely Powerful Analgesic-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of 14-Alkoxymorphinans. 20. 14-Phenylpropoxymetopon: An Extremely Powerful Analgesic

Published:2003-08-14 Issue:19 Volume:46 Page:4182-4187
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Schütz Johannes¹,Spetea Mariana¹,Koch Martin¹,Aceto Mario D.¹,Harris Louis S.¹,Coop Andrew¹,Schmidhammer Helmut¹

Affiliation:

1. Department of Pharmaceutical Chemistry, Institute of Pharmacy, University of Innsbruck, Innrain 52a, A-6020 Innsbruck, Austria, Department of Pharmacology and Toxicology, Institute of Pharmacy, University of Innsbruck, Peter-Mayr-Strasse 1, A-6020 Innsbruck, Austria, Department of Pharmacology and Toxicology, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 23298-0613, Department of Pharmaceutical Sciences, University of Maryland, School of Pharmacy, Baltimore, Maryland...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030878b

Reference36 articles.

1. Incomplete cross tolerance and multiple mu opioid peptide receptors

2. The pharmacological basis of contemporary pain management

3. Highly potent novel opioid receptor agonist in the 14-alkoxymetopon series

4. Binding characteristics of [3H]14-methoxymetopon, a high affinity u-opioid receptor agonist

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