Molecular Docking, Molecular Dynamics, and Structure–Activity Relationship Explorations of 14-Oxygenated N-Methylmorphinan-6-ones as Potent μ-Opioid Receptor Agonists-Reference-Cited by-同舟云学术

Molecular Docking, Molecular Dynamics, and Structure–Activity Relationship Explorations of 14-Oxygenated N-Methylmorphinan-6-ones as Potent μ-Opioid Receptor Agonists

Published:2017-02-09 Issue:6 Volume:8 Page:1327-1337
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Noha Stefan M.¹,Schmidhammer Helmut²,Spetea Mariana²^ORCID

Affiliation:

1. Computer-Aided Molecular Design (CAMD) Group, Department of Pharmaceutical Chemistry, Institute of Pharmacy and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria

2. Opioid Research Group, Department of Pharmaceutical Chemistry, Institute of Pharmacy and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria

Funder

Austrian Science Fund

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

http://pubs.acs.org/doi/pdf/10.1021/acschemneuro.6b00460

Reference56 articles.

1. Mu Opioids and Their Receptors: Evolution of a Concept

2. The chemical and pharmacological importance of morphine analogues

3. Synthesis of 14-Alkoxymorphinan Derivatives and Their Pharmacological Actions

4. The µ Opioid Receptor and Ligands Acting at the µ Opioid Receptor, as Therapeutics and Potential Therapeutics

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