(2E)-5-[3-[(Phenylsulfonyl)amino]phenyl]- pent-2-en-4-ynohydroxamic Acid and Its Derivatives as Novel and Potent Inhibitors of ras Transformation
Author:
Affiliation:
1. Shionogi Research Laboratories, Shionogi & Co., Ltd., Fukushima-ku, Osaka 553, Japan
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm960174k
Reference9 articles.
1. The product of ras is a GTPase and the T24 oncogenic mutant is deficient in this activity
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3. Identification of Ras farnesyltransferase inhibitors by microbial screening.
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