Pharmacokinetic/Pharmacodynamic Model-Guided Identification of Hypoxia-Selective 1,2,4-Benzotriazine 1,4-Dioxides with Antitumor Activity: The Role of Extravascular Transport-Reference-Cited by-同舟云学术

Pharmacokinetic/Pharmacodynamic Model-Guided Identification of Hypoxia-Selective 1,2,4-Benzotriazine 1,4-Dioxides with Antitumor Activity: The Role of Extravascular Transport

Published:2007-11-15 Issue:25 Volume:50 Page:6392-6404
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hay Michael P.¹,Hicks Kevin O.¹,Pruijn Frederik B.¹,Pchalek Karin¹,Siim Bronwyn G.¹,Wilson William R.¹,Denny William A.¹

Affiliation:

1. Auckland Cancer Society Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Auckland 1003, New Zealand

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm070670g

Reference59 articles.

1. Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck

2. Oxygenation predicts radiation response and survival in patients with cervix cancer

3. Endogenous Markers of Two Separate Hypoxia Response Pathways (hypoxia inducible factor 2 alpha and carbonic anhydrase 9) Are Associated With Radiotherapy Failure in Head and Neck Cancer Patients Recruited in the CHART Randomized Trial

4. Conventional cancer therapy: promise broken or promise delayed?

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