First Total Synthesis of (−)-Ichthyothereol and Its Acetate

Author:

Mukai Chisato1,Miyakoshi Naoki1,Hanaoka Miyoji1

Affiliation:

1. Faculty of Pharmaceutical Sciences, Kanazawa University, Takara-machi 13-1, Kanazawa 920-0934, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Reference21 articles.

1. Several reports on isolation of ichthyothereol and its acetate were also recorded:  (a) Gorinsky, C.; Templeton, W.; Zaidi, S. A. H.Lloydia1973,36, 352. (b) Czerson, H.; Bohlmann, F.; Stuessy, T. F.; Fischer, N. H.Phytochemistry1979,18, 257. (c) Bohlmann, F.; Borthakur, N.; King, R. M.; Robinson, H.Phytochemistry1982,21, 1793. (d) Lam, J.; Christensen, L. P.; Thomasen, T.Phytochemistry1991,30, 515.

2. Ichthyothereol and Its Acetate, the Active Polyacetylene Constituents of Ichthyothere terminalis (Spreng.) Malme, a Fish Poison from the Lower Amazon1,2

3. Regioselective and stereospecific formation of 2-ethynyl-3-hydroxytetrahydropyran derivatives via 6-endo ring closure

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