Ethnopharmacology, Phytochemistry, and Pharmacology of Pyrethrum
tatsienense (Bureau & Franch.) Ling ex C. Shih: A Comprehensive Review
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Published:2023-08
Issue:10
Volume:26
Page:1822-1835
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ISSN:1386-2073
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Container-title:Combinatorial Chemistry & High Throughput Screening
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language:en
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Short-container-title:CCHTS
Author:
Zhong Guo-Yue1, Ma Qin-Ge1, Wei Rong-Rui1, Wu Guang1, Guan Yang23, Chen Jie1, Zhu Mei-Ning1, Qiu Yong-Wei1, Zhu Cai-Qing4, Wu Yong-Zhong5
Affiliation:
1. Research Center of Natural Resources of Chinese Medicinal Materials and Ethnic Medicine & Key Laboratory of
Modern Preparation of Traditional Chinese Medicine of Ministry of Education & Laboratory Service Center, Jiangxi
University of Traditional Chinese Medicine, Nanchang, 330004, P.R. China 2. Science and Technology College, Jiangxi
University of Traditional Chinese Medicine, Nanchang, 330004, P.R. China 3. College of Chemistry and Pharmaceutical
Engineering, Nanyang Normal University, Nanyang 473061, China 4. Laboratory of Natural Pharmaceutical Chemistry,
Jiangxi Medical Device Testing Center, Nanchang, 330029, P.R. China 5. Laboratory of Natural Pharmaceutical
Chemistry, Jiangxi Puzheng Pharmaceutical Co., Ltd., Ji’an, 331400, P.R. China
Abstract
Background:
Pyrethrum tatsienense (Bureau & Franch.) Ling ex C. Shih (PTLCS) belongs
to the family Compositae, which is a perennial medicinal plant mainly distributed in the
Qinghai-Tibet Plateau of China. This review provides a comprehensive summary of the ethnopharmacology,
phytochemistry, and pharmacology of PTLCS. This review offers valuable references
and guidance for researching PTLCS in depth.
Methods:
The related references of PTLCS were retrieved from an online database, such as Web of
Science, Google Scholar, SciFinder, PubMed, SpringLink, Elsevier, Willy, CNKI, and so on.
Results:
PTLCS is widely reported for treating headaches, head injuries, traumatic injuries, anabrosis,
impetigo, hepatitis, and other diseases in the medical field. Phytochemical research revealed
that this plant contained flavonoid aglycones, flavonoid glycosides, xanthones, triterpenoids, coumarins,
polyacetylenes, volatile oils, and other compounds. Meanwhile, PTLCS exhibited extensive
pharmacological activities including anti-cardiac ischemia, anti-hypoxia, hepatoprotective, anti-
inflammatory and analgesic, and antioxidant activities.
Conclusions:
PTLCS is widely used as a Tibetan medicine, which has a variety of chemicals with
diverse bioactivities. Therefore, further studies are necessary to perform on the PTLCS to assay biological
activities, discover their bioactive constituents, and reveal pharmacological mechanisms.
This review may supply an important theoretical basis and valuable reference for in-depth research
and exploitations of PTLCS.
Publisher
Bentham Science Publishers Ltd.
Subject
Organic Chemistry,Computer Science Applications,Drug Discovery,General Medicine
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