Screening Methods to Identify Indole Derivatives That Protect against Reactive Oxygen Species Induced Tryptophan Oxidation in Proteins
Author:
Affiliation:
1. Late Stage Pharmaceutical Development, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/mp4007375
Reference46 articles.
1. Chemical instability of protein pharmaceuticals: Mechanisms of oxidation and strategies for stabilization
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4. Protein drug stability: a formulation challenge
5. Fenton chemistry in biology and medicine
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